Many gamers have reported that the latest Mass Effect 3 title update, which purports to fix the facial import problems that plagued the original release, is causing the game to crash when accessing the EA servers on Xbox 360. Some players find themselves unable to even access the main menu, and have had to resort to workarounds such as clearing the cache files or running the game offline.
BioWare is aware of the issues, and urges those affected to provide details. With enough feedback, they ought to be able to fix it.
We believe that this issue only affects a minority of Xbox 360 players, but do get in touch if you've encountered these problems.